GABA(B) Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure

Autoantibodies to the γ-aminobutyric acid receptor, subtype B (GABA(B)), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABA(B) encephalitis presenting with encephalopa...

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Autores principales: Loftspring, Matthew C., Landsness, Eric, Wooliscroft, Lindsey, Rudock, Robert, Jo, Sally, Patel, Kevin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644823/
https://www.ncbi.nlm.nih.gov/pubmed/26609456
http://dx.doi.org/10.1155/2015/812035
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author Loftspring, Matthew C.
Landsness, Eric
Wooliscroft, Lindsey
Rudock, Robert
Jo, Sally
Patel, Kevin R.
author_facet Loftspring, Matthew C.
Landsness, Eric
Wooliscroft, Lindsey
Rudock, Robert
Jo, Sally
Patel, Kevin R.
author_sort Loftspring, Matthew C.
collection PubMed
description Autoantibodies to the γ-aminobutyric acid receptor, subtype B (GABA(B)), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABA(B) encephalitis presenting with encephalopathy, status epilepticus, dysautonomia, and acute heart failure. To our knowledge, heart failure and dysautonomia have not yet been reported with this syndrome.
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spelling pubmed-46448232015-11-25 GABA(B) Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure Loftspring, Matthew C. Landsness, Eric Wooliscroft, Lindsey Rudock, Robert Jo, Sally Patel, Kevin R. Case Rep Neurol Med Case Report Autoantibodies to the γ-aminobutyric acid receptor, subtype B (GABA(B)), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABA(B) encephalitis presenting with encephalopathy, status epilepticus, dysautonomia, and acute heart failure. To our knowledge, heart failure and dysautonomia have not yet been reported with this syndrome. Hindawi Publishing Corporation 2015 2015-11-02 /pmc/articles/PMC4644823/ /pubmed/26609456 http://dx.doi.org/10.1155/2015/812035 Text en Copyright © 2015 Matthew C. Loftspring et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Loftspring, Matthew C.
Landsness, Eric
Wooliscroft, Lindsey
Rudock, Robert
Jo, Sally
Patel, Kevin R.
GABA(B) Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title GABA(B) Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_full GABA(B) Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_fullStr GABA(B) Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_full_unstemmed GABA(B) Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_short GABA(B) Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_sort gaba(b) encephalitis: a fifty-two-year-old man with seizures, dysautonomia, and acute heart failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644823/
https://www.ncbi.nlm.nih.gov/pubmed/26609456
http://dx.doi.org/10.1155/2015/812035
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