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IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes
The unfolded protein response (UPR) not only resolves endoplasmic reticulum (ER) stress, but also regulates cellular physiological functions. In this study, we first linked the UPR to the physiological roles of brown adipose tissue (BAT). BAT is one of the tissues that control energy homeostasis in...
Autores principales: | Asada, Rie, Kanemoto, Soshi, Matsuhisa, Koji, Hino, Kenta, Cui, Min, Cui, Xiang, Kaneko, Masayuki, Imaizumi, Kazunori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644985/ https://www.ncbi.nlm.nih.gov/pubmed/26568450 http://dx.doi.org/10.1038/srep16580 |
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