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Crystal structure of 5-(5-chloro-2-hydroxybenzoyl)-2-(2-methyl-1H-indol-3-yl)nicotinonitrile
In the title compound, C(22)H(14)ClN(3)O(2), the indole unit is essentially coplanar, with a maximum deviation of 0.035 Å for the C atom bearing the methyl group. The central pyridine ring is inclined to the indole ring system by 43.7 (1)°. The dihedral angle between the phenyl ring and the indole r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645016/ https://www.ncbi.nlm.nih.gov/pubmed/26594546 http://dx.doi.org/10.1107/S2056989015018058 |
Sumario: | In the title compound, C(22)H(14)ClN(3)O(2), the indole unit is essentially coplanar, with a maximum deviation of 0.035 Å for the C atom bearing the methyl group. The central pyridine ring is inclined to the indole ring system by 43.7 (1)°. The dihedral angle between the phenyl ring and the indole ring system is 15.7 (2)°, while that between the phenyl ring and the central pyridine ring is 46.3 (1)°. The molecular structure is stabilized by an intramolecular O—H⋯O hydrogen bonding, forming an S(6) ring motif. In the crystal, molecules are linked via pairs of N—H⋯N hydrogen bonds, forming inversion dimers with an R (2) (2)(16) ring motif. The crystal structure also features C—H⋯π and π–π interactions [centroid–centroid separation = 3.688 (1) Å]. |
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