Crystal structure of 3′-(1H-indole-3-carbon­yl)-1′-methyl-2-oxo-4′-(4-oxo-4H-chromen-3-yl)spiro­[indoline-3,2′-pyrrolidine]-3′-carbo­nitrile

In the title compound, C(31)H(22)N(4)O(4), the pyrrolidine ring adopts a twist conformation on the N—CH(2) bond. The indolin-2-one and the 1H-indole rings are nearly planar (r.m.s. deviations = 0.06 and 0.011 Å, respectively) and are inclined to one another by 34.19 (9)°. The chromene ring system is...

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Autores principales: Savithri, M. P., Raja, R., Kathirvelan, D., Reddy, B. S. R., SubbiahPandi, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Data Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645027/
https://www.ncbi.nlm.nih.gov/pubmed/26594587
http://dx.doi.org/10.1107/S2056989015020174
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author Savithri, M. P.
Raja, R.
Kathirvelan, D.
Reddy, B. S. R.
SubbiahPandi, A.
author_facet Savithri, M. P.
Raja, R.
Kathirvelan, D.
Reddy, B. S. R.
SubbiahPandi, A.
author_sort Savithri, M. P.
collection PubMed
description In the title compound, C(31)H(22)N(4)O(4), the pyrrolidine ring adopts a twist conformation on the N—CH(2) bond. The indolin-2-one and the 1H-indole rings are nearly planar (r.m.s. deviations = 0.06 and 0.011 Å, respectively) and are inclined to one another by 34.19 (9)°. The chromene ring system is also nearly planar (r.m.s. deviation = 0.029 Å). It is almost normal to the 1H-indole ring system, with a dihedral angle of 88.71 (8)°, and is inclined to the indolin-2-one ring system by 72.76 (8)°. In the crystal, mol­ecules are linked via N—H⋯O hydrogen bonds, forming slabs parallel to (10-1). The slabs are linked by C—H⋯O hydrogen bonds, forming a three-dimensional structure.
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spelling pubmed-46450272015-11-20 Crystal structure of 3′-(1H-indole-3-carbon­yl)-1′-methyl-2-oxo-4′-(4-oxo-4H-chromen-3-yl)spiro­[indoline-3,2′-pyrrolidine]-3′-carbo­nitrile Savithri, M. P. Raja, R. Kathirvelan, D. Reddy, B. S. R. SubbiahPandi, A. Acta Crystallogr E Crystallogr Commun Data Reports In the title compound, C(31)H(22)N(4)O(4), the pyrrolidine ring adopts a twist conformation on the N—CH(2) bond. The indolin-2-one and the 1H-indole rings are nearly planar (r.m.s. deviations = 0.06 and 0.011 Å, respectively) and are inclined to one another by 34.19 (9)°. The chromene ring system is also nearly planar (r.m.s. deviation = 0.029 Å). It is almost normal to the 1H-indole ring system, with a dihedral angle of 88.71 (8)°, and is inclined to the indolin-2-one ring system by 72.76 (8)°. In the crystal, mol­ecules are linked via N—H⋯O hydrogen bonds, forming slabs parallel to (10-1). The slabs are linked by C—H⋯O hydrogen bonds, forming a three-dimensional structure. International Union of Crystallography 2015-10-31 /pmc/articles/PMC4645027/ /pubmed/26594587 http://dx.doi.org/10.1107/S2056989015020174 Text en © Savithri et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Data Reports
Savithri, M. P.
Raja, R.
Kathirvelan, D.
Reddy, B. S. R.
SubbiahPandi, A.
Crystal structure of 3′-(1H-indole-3-carbon­yl)-1′-methyl-2-oxo-4′-(4-oxo-4H-chromen-3-yl)spiro­[indoline-3,2′-pyrrolidine]-3′-carbo­nitrile
title Crystal structure of 3′-(1H-indole-3-carbon­yl)-1′-methyl-2-oxo-4′-(4-oxo-4H-chromen-3-yl)spiro­[indoline-3,2′-pyrrolidine]-3′-carbo­nitrile
title_full Crystal structure of 3′-(1H-indole-3-carbon­yl)-1′-methyl-2-oxo-4′-(4-oxo-4H-chromen-3-yl)spiro­[indoline-3,2′-pyrrolidine]-3′-carbo­nitrile
title_fullStr Crystal structure of 3′-(1H-indole-3-carbon­yl)-1′-methyl-2-oxo-4′-(4-oxo-4H-chromen-3-yl)spiro­[indoline-3,2′-pyrrolidine]-3′-carbo­nitrile
title_full_unstemmed Crystal structure of 3′-(1H-indole-3-carbon­yl)-1′-methyl-2-oxo-4′-(4-oxo-4H-chromen-3-yl)spiro­[indoline-3,2′-pyrrolidine]-3′-carbo­nitrile
title_short Crystal structure of 3′-(1H-indole-3-carbon­yl)-1′-methyl-2-oxo-4′-(4-oxo-4H-chromen-3-yl)spiro­[indoline-3,2′-pyrrolidine]-3′-carbo­nitrile
title_sort crystal structure of 3′-(1h-indole-3-carbon­yl)-1′-methyl-2-oxo-4′-(4-oxo-4h-chromen-3-yl)spiro­[indoline-3,2′-pyrrolidine]-3′-carbo­nitrile
topic Data Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645027/
https://www.ncbi.nlm.nih.gov/pubmed/26594587
http://dx.doi.org/10.1107/S2056989015020174
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