Genome Sequence of Complex HIV-1 Unique Recombinant Forms Sharing a Common Recombination Breakpoint Identified in Malaysia

Three strains of HIV-1 unique recombinant forms (URFs) descended from subtypes B, B′, and CRF01_AE were identified among people who inject drugs in Kuala Lumpur, Malaysia. These three URFs shared a common recombination breakpoint in the reverse transcriptase region, indicating frequent linkage withi...

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Detalles Bibliográficos
Autores principales: Cheong, Hui Ting, Ng, Kim Tien, Ong, Lai Yee, Takebe, Yutaka, Chan, Kok Gan, Koh, Clayton, Al-Darraji, Haider Abdulrazzaq Abed, Kamarulzaman, Adeeba, Tee, Kok Keng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645192/
https://www.ncbi.nlm.nih.gov/pubmed/26543107
http://dx.doi.org/10.1128/genomeA.01220-15
Descripción
Sumario:Three strains of HIV-1 unique recombinant forms (URFs) descended from subtypes B, B′, and CRF01_AE were identified among people who inject drugs in Kuala Lumpur, Malaysia. These three URFs shared a common recombination breakpoint in the reverse transcriptase region, indicating frequent linkage within the drug-injecting networks in Malaysia.

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