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Antiviral RNA Interference against Orsay Virus Is neither Systemic nor Transgenerational in Caenorhabditis elegans

Antiviral RNA-mediated silencing (RNA interference [RNAi]) acts as a powerful innate immunity defense in plants, invertebrates, and mammals. In Caenorhabditis elegans, RNAi is systemic; i.e., RNAi silencing signals can move between cells and tissues. Furthermore, RNAi effects can be inherited transg...

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Detalles Bibliográficos
Autores principales: Ashe, Alyson, Sarkies, Peter, Le Pen, Jérémie, Tanguy, Mélanie, Miska, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645334/
https://www.ncbi.nlm.nih.gov/pubmed/26401037
http://dx.doi.org/10.1128/JVI.03664-14