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Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2)
The glucagon and glucagon-like peptide-1 (GLP-1) receptors play important, opposing roles in regulating blood glucose levels. Consequently, these receptors have been identified as targets for novel diabetes treatments. However, drugs acting at the GLP-1 receptor, although having clinical efficacy, h...
Autores principales: | Weston, Cathryn, Lu, Jing, Li, Naichang, Barkan, Kerry, Richards, Gareth O., Roberts, David J., Skerry, Timothy M., Poyner, David, Pardamwar, Meenakshi, Reynolds, Christopher A., Dowell, Simon J., Willars, Gary B., Ladds, Graham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645630/ https://www.ncbi.nlm.nih.gov/pubmed/26198634 http://dx.doi.org/10.1074/jbc.M114.624601 |
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