Microbial Disruption of Autophagy Alters Expression of the RISC Component AGO2, a Critical Regulator of the miRNA Silencing Pathway

Autophagy is implicated in Crohn's disease (CD) pathogenesis. Recent evidence suggests autophagy regulates the microRNA (miRNA)-induced silencing complex (miRISC). Therefore, autophagy may play a novel role in CD by regulating expression of miRISC, thereby altering miRNA silencing. As microbes...

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Detalles Bibliográficos
Autores principales: Sibony, Michal, Abdullah, Majd, Greenfield, Laura, Raju, Deepa, Wu, Ted, Rodrigues, David M., Galindo-Mata, Esther, Mascarenhas, Heidi, Philpott, Dana J., Silverberg, Mark S., Jones, Nicola L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Original Basic Science Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645954/
https://www.ncbi.nlm.nih.gov/pubmed/26332312
http://dx.doi.org/10.1097/MIB.0000000000000553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645954/
https://www.ncbi.nlm.nih.gov/pubmed/26332312
http://dx.doi.org/10.1097/MIB.0000000000000553

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