Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment

Detalles Bibliográficos
Autores principales: Horton, Brendan, Williams, Jason B, Spranger, Stefani, Gajewski, Thomas F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Oral Presentation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646107/
http://dx.doi.org/10.1186/2051-1426-3-S2-O10
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author Horton, Brendan
Williams, Jason B
Spranger, Stefani
Gajewski, Thomas F
author_facet Horton, Brendan
Williams, Jason B
Spranger, Stefani
Gajewski, Thomas F
author_sort Horton, Brendan
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spelling pubmed-46461072015-11-20 Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment Horton, Brendan Williams, Jason B Spranger, Stefani Gajewski, Thomas F J Immunother Cancer Oral Presentation BioMed Central 2015-11-04 /pmc/articles/PMC4646107/ http://dx.doi.org/10.1186/2051-1426-3-S2-O10 Text en Copyright © 2015 Horton et al. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Oral Presentation
Horton, Brendan
Williams, Jason B
Spranger, Stefani
Gajewski, Thomas F
Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment
title Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment
title_full Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment
title_fullStr Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment
title_full_unstemmed Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment
title_short Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment
title_sort agonist anti-4-1bb plus neutralizing anti-ctla-4 or -pd-l1 synergize to promote tumor regression by rescuing dying dysfunctional cd8+ t cells within the tumor microenvironment
topic Oral Presentation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646107/
http://dx.doi.org/10.1186/2051-1426-3-S2-O10
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