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2-DG-Regulated RIP and c-FLIP Effect on Liver Cancer Cell Apoptosis Induced by TRAIL

BACKGROUND: Cancer cells survival depends on glucose metabolism and ATP. Inhibiting glucose metabolism is a possible anticancer treatment. The phosphorylation of 2-deoxy-D-glucose (2-DG), which is a glycogen analogue, seriously affects the normal glycometabolism phosphorylation process, leading to A...

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Detalles Bibliográficos
Autores principales: Zhang, Yuping, Huang, Feizhou, Wang, Jian, Luo, Hongwu, Wang, Zhichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646230/
https://www.ncbi.nlm.nih.gov/pubmed/26552967
http://dx.doi.org/10.12659/MSM.895034

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