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Calpain Cleaves Most Components in the Multiple Aminoacyl-tRNA Synthetase Complex and Affects Their Functions
Nine aminoacyl-tRNA synthetases (aaRSs) and three scaffold proteins form a super multiple aminoacyl-tRNA synthetase complex (MSC) in the human cytoplasm. Domains that have been added progressively to MSC components during evolution are linked by unstructured flexible peptides, producing an elongated...
Autores principales: | Lei, Hui-Yan, Zhou, Xiao-Long, Ruan, Zhi-Rong, Sun, Wei-Cheng, Eriani, Gilbert, Wang, En-Duo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646279/ https://www.ncbi.nlm.nih.gov/pubmed/26324710 http://dx.doi.org/10.1074/jbc.M115.681999 |
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