Cargando…

Self-assembly Is Prerequisite for Catalysis of Fe(II) Oxidation by Catalytically Active Subunits of Ferritin

Fe(III) storage by ferritin is an essential process of the iron homeostasis machinery. It begins by translocation of Fe(II) from outside the hollow spherical shape structure of the protein, which is formed as the result of self-assembly of 24 subunits, to a di-iron binding site, the ferroxidase cent...

Descripción completa

Detalles Bibliográficos
Autores principales: Ebrahimi, Kourosh Honarmand, Hagedoorn, Peter-Leon, Hagen, Wilfred R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646333/
https://www.ncbi.nlm.nih.gov/pubmed/26370076
http://dx.doi.org/10.1074/jbc.M115.678375