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Self-assembly Is Prerequisite for Catalysis of Fe(II) Oxidation by Catalytically Active Subunits of Ferritin
Fe(III) storage by ferritin is an essential process of the iron homeostasis machinery. It begins by translocation of Fe(II) from outside the hollow spherical shape structure of the protein, which is formed as the result of self-assembly of 24 subunits, to a di-iron binding site, the ferroxidase cent...
Autores principales: | Ebrahimi, Kourosh Honarmand, Hagedoorn, Peter-Leon, Hagen, Wilfred R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646333/ https://www.ncbi.nlm.nih.gov/pubmed/26370076 http://dx.doi.org/10.1074/jbc.M115.678375 |
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