The Deubiquitinating Enzyme UBPY Is Required for Lysosomal Biogenesis and Productive Autophagy in Drosophila

Autophagy is a catabolic process that delivers cytoplasmic components to the lysosomes. Protein modification by ubiquitination is involved in this pathway: it regulates the stability of autophagy regulators such as BECLIN-1 and it also functions as a tag targeting specific substrates to autophagosom...

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Detalles Bibliográficos
Autores principales: Jacomin, Anne-Claire, Bescond, Amandine, Soleilhac, Emmanuelle, Gallet, Benoît, Schoehn, Guy, Fauvarque, Marie-Odile, Taillebourg, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646453/
https://www.ncbi.nlm.nih.gov/pubmed/26571504
http://dx.doi.org/10.1371/journal.pone.0143078

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