Genome-Wide Locations of Potential Epimutations Associated with Environmentally Induced Epigenetic Transgenerational Inheritance of Disease Using a Sequential Machine Learning Prediction Approach

Environmentally induced epigenetic transgenerational inheritance of disease and phenotypic variation involves germline transmitted epimutations. The primary epimutations identified involve altered differential DNA methylation regions (DMRs). Different environmental toxicants have been shown to promo...

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Detalles Bibliográficos
Autores principales: Haque, M. Muksitul, Holder, Lawrence B., Skinner, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646459/
https://www.ncbi.nlm.nih.gov/pubmed/26571271
http://dx.doi.org/10.1371/journal.pone.0142274

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