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Dynamic Bayesian Network Modeling of the Interplay between EGFR and Hedgehog Signaling
Aberrant activation of sonic Hegdehog (SHH) signaling has been found to disrupt cellular differentiation in many human cancers and to increase proliferation. The SHH pathway is known to cross-talk with EGFR dependent signaling. Recent studies experimentally addressed this interplay in Daoy cells, wh...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646463/ https://www.ncbi.nlm.nih.gov/pubmed/26571415 http://dx.doi.org/10.1371/journal.pone.0142646 |