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Head-to-Head Comparison of Soluble vs. Qβ VLP Circumsporozoite Protein Vaccines Reveals Selective Enhancement of NANP Repeat Responses
Circumsporozoite protein (CSP) of Plasmodium falciparum is a promising malaria vaccine target. RTS,S, the most advanced malaria vaccine candidate consists of the central NANP repeat and carboxy-terminal region of CSP displayed on a hepatitis B virus-like particle (VLP). To build upon the success of...
Autores principales: | Khan, Farhat, Porter, Mike, Schwenk, Robert, DeBot, Margot, Saudan, Philippe, Dutta, Sheetij |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646581/ https://www.ncbi.nlm.nih.gov/pubmed/26571021 http://dx.doi.org/10.1371/journal.pone.0142035 |
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