Cargando…

Osteoprotegerin Induces Apoptosis of Osteoclasts and Osteoclast Precursor Cells via the Fas/Fas Ligand Pathway

Osteoprotegerin (OPG) is known to inhibit differentiation and activation of osteoclasts (OCs) by functioning as a decoy receptor blocking interactions between RANK and RANKL. However, the exact role of OPG in the survival/apoptosis of OCs remains unclear. OPG caused increased rates of apoptosis of b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Wei, Xu, Chao, Zhao, Hongyan, Xia, Pengpeng, Song, Ruilong, Gu, Jianhong, Liu, Xuezhong, Bian, Jianchun, Yuan, Yan, Liu, Zongping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646684/ https://www.ncbi.nlm.nih.gov/pubmed/26571489 http://dx.doi.org/10.1371/journal.pone.0142519

Ejemplares similares

Suppression of AMP‐activated protein kinase reverses osteoprotegerin‐induced inhibition of osteoclast differentiation by reducing autophagy
por: Tong, Xishuai, et al.
Publicado: (2019)

Beclin-1-mediated Autophagy Protects Against Cadmium-activated Apoptosis via the Fas/FasL Pathway in Primary Rat Proximal Tubular Cell Culture
por: Liu, Gang, et al.
Publicado: (2017)

Involvement of the Ca(2+) signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation
por: Fu, Yingxiao, et al.
Publicado: (2015)

Cadmium-induced apoptosis in neuronal cells is mediated by Fas/FasL-mediated mitochondrial apoptotic signaling pathway
por: Yuan, Yan, et al.
Publicado: (2018)

The Mechanism of Osteoprotegerin-Induced Osteoclast Pyroptosis In Vitro
por: Zhu, Jiaqiao, et al.
Publicado: (2023)

Overexpression of c‐Fos reverses osteoprotegerin‐mediated suppression of osteoclastogenesis by increasing the Beclin1‐induced autophagy
por: Tong, Xishuai, et al.
Publicado: (2020)

Potential mechanisms of osteoprotegerin-induced damage to osteoclast adhesion structures via P2X7R-mediated MAPK signaling
por: Ma, Yonggang, et al.
Publicado: (2022)

Vitamin D Inhibition of TRPV5 Expression During Osteoclast Differentiation
por: Gu, Jianhong, et al.
Publicado: (2019)

The Ligand for Osteoprotegerin (OPGL) Directly Activates Mature Osteoclasts
por: Burgess, Teresa L., et al.
Publicado: (1999)

Apoptosis role of FAS/FAS ligand system in the regulation of myelopoiesis.
por: Alenzi, Faris Q., et al.
Publicado: (2005)

Expression Profile of Fas-Fas Ligand in Spiral Ganglion Cells During Apoptosis
por: Gu, Tae Woo, et al.
Publicado: (2014)

The Role of Galectin-3 in 1α,25(OH)(2)D(3)-Regulated Osteoclast Formation from White Leghorn Chickens In Vitro
por: Gu, Jianhong, et al.
Publicado: (2021)

Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids
Publicado: (1995)

Differential Induction of Apoptosis by Fas–Fas Ligand Interactions in Human Monocytes and Macrophages
por: Kiener, Peter A., et al.
Publicado: (1997)

Involvement of the Fas and Fas ligand in testicular germ cell apoptosis by zearalenone in rat
por: Jee, Youngheun, et al.
Publicado: (2010)

Disruption of Fas-Fas Ligand Signaling, Apoptosis, and Innate Immunity by Bacterial Pathogens
por: Caulfield, Adam J., et al.
Publicado: (2014)

The Fas/Fas Ligand Death Receptor Pathway Contributes to Phenylalanine-Induced Apoptosis in Cortical Neurons
por: Huang, Xiaodong, et al.
Publicado: (2013)

Origin of Osteoclasts: Osteoclast Precursor Cells
por: Tsai, Jefferson, et al.
Publicado: (2023)

Sex Hormones, Apoptosis and the Fas/Fas Ligand System in Normal Endometrial Tissue Remodeling
por: Mor, Gil, et al.
Publicado: (2001)

Inhibitory effects of osteoprotegerin on osteoclast formation and function under serum-free conditions
por: Fu, Ying-Xiao, et al.
Publicado: (2013)

Understanding the role of Fas-Fas ligand system in bone
por: Marusic, Ana, et al.
Publicado: (2012)

Differential expressions of Fas and Fas ligand in human placenta.
por: Roh, Cheong-Rae, et al.
Publicado: (2002)

Role of autophagy in cadmium-induced apoptosis of primary rat osteoblasts
por: Liu, Wei, et al.
Publicado: (2016)

Impairment of Fas-ligand–caveolin-1 interaction inhibits Fas-ligand translocation to rafts and Fas-ligand-induced cell death
por: Glukhova, Xenia A., et al.
Publicado: (2018)

Purification and characterization of the Fas-ligand that induces apoptosis
Publicado: (1994)

Membrane-bound but not Secreted Fas Ligand Is Essential for Fas-Induced Apoptosis and Prevention of Autoimmunity and Cancer
por: O' Reilly, Lorraine A., et al.
Publicado: (2009)

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
Publicado: (1996)

Associations of serum soluble Fas and Fas ligand (FasL) with outcomes in systemic lupus erythematosus
por: Vincent, Fabien B, et al.
Publicado: (2020)

Fas and Fas Ligand Interactions Suppress Melanoma Lung Metastasis
por: Owen-Schaub, Laurie B., et al.
Publicado: (1998)

Prognostic value of the Fas/Fas ligand system in breast cancer
por: Bębenek, Marek, et al.
Publicado: (2013)

Fas–Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis
por: Volpe, Elisabetta, et al.
Publicado: (2016)

The Fas/FasL System in Reproduction: Survival and Apoptosis
por: Mor, Gil, et al.
Publicado: (2002)

Major vault protein (MVP) suppresses aging- and estrogen deficiency-related bone loss through Fas-mediated apoptosis in osteoclasts
por: Wang, Ruobing, et al.
Publicado: (2023)

Mesenchymal stem cells inhibit multiple myeloma cells via the Fas/Fas ligand pathway
por: Atsuta, Ikiru, et al.
Publicado: (2013)

Intracellular Fas ligand in normal and malignant breast epithelium does not induce apoptosis in Fas-sensitive cells
por: Ragnarsson, G B, et al.
Publicado: (2000)

FAS and FAS-Ligand Promoter Polymorphisms in Hepatitis B Virus Infection
por: Mohammadi, Asadollah, et al.
Publicado: (2015)

The relationship between Fas and Fas ligand gene polymorphism and preeclampsia risk
por: Wang, Tingting, et al.
Publicado: (2019)

P2X7 receptor knockdown suppresses osteoclast differentiation by inhibiting autophagy and Ca(2+)/calcineurin signaling
por: Ma, Yonggang, et al.
Publicado: (2022)

Activation of the Fas/Fas ligand pathway in hypertensive renal disease in Dahl/Rapp rats
por: Sanders, Paul W, et al.
Publicado: (2002)

Tumour-induced apoptosis in human mesothelial cells: a mechanism of peritoneal invasion by Fas Ligand/Fas interaction
por: Heath, R M, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_eog4idsfcvf3ma8ovsofeo92r8