Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease

Chronic graft-versus-host disease (cGVHD) is one of the most important causes of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (aHSCT). Occurring in 30% to 70% of patients, cGVHD has a median time to onset of 4 to 6 months and most cases present within 2 years afte...

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Detalles Bibliográficos
Autores principales: Gunes, Gursel, Demiroglu, Haluk, Goker, Hakan, Malkan, Umit Yavuz, Eliacik, Eylem, Yayar, Okan, Buyukasik, Yahya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646988/
https://www.ncbi.nlm.nih.gov/pubmed/26613052
http://dx.doi.org/10.1155/2015/692175
Descripción
Sumario:Chronic graft-versus-host disease (cGVHD) is one of the most important causes of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (aHSCT). Occurring in 30% to 70% of patients, cGVHD has a median time to onset of 4 to 6 months and most cases present within 2 years after aHSCT. Here, we present a patient transplanted at the age of 55 who developed refractory cutaneous cGVHD more than 5.5 years after aHSCT.

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