Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease

Chronic graft-versus-host disease (cGVHD) is one of the most important causes of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (aHSCT). Occurring in 30% to 70% of patients, cGVHD has a median time to onset of 4 to 6 months and most cases present within 2 years afte...

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Autores principales: Gunes, Gursel, Demiroglu, Haluk, Goker, Hakan, Malkan, Umit Yavuz, Eliacik, Eylem, Yayar, Okan, Buyukasik, Yahya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646988/
https://www.ncbi.nlm.nih.gov/pubmed/26613052
http://dx.doi.org/10.1155/2015/692175
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author Gunes, Gursel
Demiroglu, Haluk
Goker, Hakan
Malkan, Umit Yavuz
Eliacik, Eylem
Yayar, Okan
Buyukasik, Yahya
author_facet Gunes, Gursel
Demiroglu, Haluk
Goker, Hakan
Malkan, Umit Yavuz
Eliacik, Eylem
Yayar, Okan
Buyukasik, Yahya
author_sort Gunes, Gursel
collection PubMed
description Chronic graft-versus-host disease (cGVHD) is one of the most important causes of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (aHSCT). Occurring in 30% to 70% of patients, cGVHD has a median time to onset of 4 to 6 months and most cases present within 2 years after aHSCT. Here, we present a patient transplanted at the age of 55 who developed refractory cutaneous cGVHD more than 5.5 years after aHSCT.
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spelling pubmed-46469882015-11-26 Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease Gunes, Gursel Demiroglu, Haluk Goker, Hakan Malkan, Umit Yavuz Eliacik, Eylem Yayar, Okan Buyukasik, Yahya Case Rep Hematol Case Report Chronic graft-versus-host disease (cGVHD) is one of the most important causes of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (aHSCT). Occurring in 30% to 70% of patients, cGVHD has a median time to onset of 4 to 6 months and most cases present within 2 years after aHSCT. Here, we present a patient transplanted at the age of 55 who developed refractory cutaneous cGVHD more than 5.5 years after aHSCT. Hindawi Publishing Corporation 2015 2015-11-03 /pmc/articles/PMC4646988/ /pubmed/26613052 http://dx.doi.org/10.1155/2015/692175 Text en Copyright © 2015 Gursel Gunes et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gunes, Gursel
Demiroglu, Haluk
Goker, Hakan
Malkan, Umit Yavuz
Eliacik, Eylem
Yayar, Okan
Buyukasik, Yahya
Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease
title Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease
title_full Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease
title_fullStr Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease
title_full_unstemmed Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease
title_short Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease
title_sort late onset and protracted course of steroid refractory chronic graft-versus-host disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646988/
https://www.ncbi.nlm.nih.gov/pubmed/26613052
http://dx.doi.org/10.1155/2015/692175
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