TLR9 ligation in pancreatic stellate cells promotes tumorigenesis

Modulation of Toll-like receptor (TLR) signaling can have protective or protumorigenic effects on oncogenesis depending on the cancer subtype and on specific inflammatory elements within the tumor milieu. We found that TLR9 is widely expressed early during the course of pancreatic transformation and...

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Detalles Bibliográficos
Autores principales: Zambirinis, Constantinos P., Levie, Elliot, Nguy, Susanna, Avanzi, Antonina, Barilla, Rocky, Xu, Yijie, Seifert, Lena, Daley, Donnele, Greco, Stephanie H., Deutsch, Michael, Jonnadula, Saikiran, Torres-Hernandez, Alejandro, Tippens, Daniel, Pushalkar, Smruti, Eisenthal, Andrew, Saxena, Deepak, Ahn, Jiyoung, Hajdu, Cristina, Engle, Dannielle D., Tuveson, David, Miller, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647258/
https://www.ncbi.nlm.nih.gov/pubmed/26481685
http://dx.doi.org/10.1084/jem.20142162

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