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Transcriptional repressor ZEB2 promotes terminal differentiation of CD8(+) effector and memory T cell populations during infection
ZEB2 is a multi-zinc-finger transcription factor known to play a significant role in early neurogenesis and in epithelial-mesenchymal transition–dependent tumor metastasis. Although the function of ZEB2 in T lymphocytes is unknown, activity of the closely related family member ZEB1 has been implicat...
Autores principales: | Omilusik, Kyla D., Best, J. Adam, Yu, Bingfei, Goossens, Steven, Weidemann, Alexander, Nguyen, Jessica V., Seuntjens, Eve, Stryjewska, Agata, Zweier, Christiane, Roychoudhuri, Rahul, Gattinoni, Luca, Bird, Lynne M., Higashi, Yujiro, Kondoh, Hisato, Huylebroeck, Danny, Haigh, Jody, Goldrath, Ananda W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647262/ https://www.ncbi.nlm.nih.gov/pubmed/26503445 http://dx.doi.org/10.1084/jem.20150194 |
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