Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis

Although much progress has been made in identifying the mechanisms that trigger endothelial activation and inflammatory cell recruitment during atherosclerosis, less is known about the intrinsic pathways that counteract these events. Here we identified NOTCH1 as an antagonist of endothelial cell (EC...

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Detalles Bibliográficos
Autores principales: Briot, Anaïs, Civelek, Mete, Seki, Atsuko, Hoi, Karen, Mack, Julia J., Lee, Stephen D., Kim, Jason, Hong, Cynthia, Yu, Jingjing, Fishbein, Gregory A., Vakili, Ladan, Fogelman, Alan M., Fishbein, Michael C., Lusis, Aldons J., Tontonoz, Peter, Navab, Mohamad, Berliner, Judith A., Iruela-Arispe, M. Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647265/
https://www.ncbi.nlm.nih.gov/pubmed/26552708
http://dx.doi.org/10.1084/jem.20150603

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