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DNAM-1 controls NK cell activation via an ITT-like motif

DNAM-1 (CD226) is an activating receptor expressed on natural killer (NK) cells, CD8(+) T cells, and other immune cells. Upon recognition of its ligands, CD155 and CD112, DNAM-1 promotes NK cell–mediated elimination of transformed and virus-infected cells. It also has a key role in expansion and mai...

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Detalles Bibliográficos
Autores principales: Zhang, Zhanguang, Wu, Ning, Lu, Yan, Davidson, Dominique, Colonna, Marco, Veillette, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647266/
https://www.ncbi.nlm.nih.gov/pubmed/26552706
http://dx.doi.org/10.1084/jem.20150792