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A Boolean network model of human gonadal sex determination

BACKGROUND: Gonadal sex determination (GSD) in humans is a complex biological process that takes place in early stages of embryonic development when the bipotential gonadal primordium (BGP) differentiates towards testes or ovaries. This decision is directed by one of two distinct pathways embedded i...

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Detalles Bibliográficos
Autores principales: Ríos, Osiris, Frias, Sara, Rodríguez, Alfredo, Kofman, Susana, Merchant, Horacio, Torres, Leda, Mendoza, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647291/
https://www.ncbi.nlm.nih.gov/pubmed/26573569
http://dx.doi.org/10.1186/s12976-015-0023-0