IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation

BACKGROUND: Local tumor control by standard fractionated radiotherapy (RT) remains poor because of tumor resistance to radiation (radioresistance). It has been suggested that cancer stem cells (CSCs) are more radioresistant than non-CSCs. In previous studies, we have shown IL-6 promotes self-renewal...

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Detalles Bibliográficos
Autores principales: Chen, Yuhchyau, Zhang, Fuquan, Tsai, Ying, Yang, Xiadong, Yang, Li, Duan, Shanzhou, Wang, Xin, Keng, Peter, Lee, Soo Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647293/
https://www.ncbi.nlm.nih.gov/pubmed/26572130
http://dx.doi.org/10.1186/s13014-015-0534-1

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