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Recombination elevates the effective evolutionary rate and facilitates the establishment of HIV-1 infection in infants after mother-to-child transmission

BACKGROUND: Previous studies have demonstrated that single HIV-1 genotypes are commonly transmitted from mother to child, but such analyses primarily used single samples from mother and child. It is possible that in a single sample, obtained early after infection, only the most replication competent...

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Detalles Bibliográficos
Autores principales: Sanborn, Keri B., Somasundaran, Mohan, Luzuriaga, Katherine, Leitner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647327/
https://www.ncbi.nlm.nih.gov/pubmed/26573574
http://dx.doi.org/10.1186/s12977-015-0222-0