Cargando…
Crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone
The title compound, C(13)H(14)NO(2)F(3), crystallises with two molecules, A and B, in the asymmetric unit, with similar conformations. The dihedral angles between the piperidine and phenyl rings are 83.76 (2) and 75.23 (2)° in molecules A and B, respectively. The bond-angle sums around the N atoms...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647357/ https://www.ncbi.nlm.nih.gov/pubmed/26594481 http://dx.doi.org/10.1107/S205698901501765X |
| _version_ | 1782401080776196096 |
|---|---|
| author | Revathi, B. K. Reuben Jonathan, D. Kalai Sevi, K. Dhanalakshmi, K. Usha, G. |
| author_facet | Revathi, B. K. Reuben Jonathan, D. Kalai Sevi, K. Dhanalakshmi, K. Usha, G. |
| author_sort | Revathi, B. K. |
| collection | PubMed |
| description | The title compound, C(13)H(14)NO(2)F(3), crystallises with two molecules, A and B, in the asymmetric unit, with similar conformations. The dihedral angles between the piperidine and phenyl rings are 83.76 (2) and 75.23 (2)° in molecules A and B, respectively. The bond-angle sums around the N atoms [359.1 and 359.7° for molecules A and B, respectively] indicate sp (2) hybridization for these atoms. In the crystal, O—H⋯O hydrogen bonds link the molecules into separate [100] chains of A and B molecules. The chains are cross-linked by C—H⋯O interactions, generating alternating (001) sheets of A and B molecules. |
| format | Online Article Text |
| id | pubmed-4647357 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-46473572015-11-20 Crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone Revathi, B. K. Reuben Jonathan, D. Kalai Sevi, K. Dhanalakshmi, K. Usha, G. Acta Crystallogr E Crystallogr Commun Data Reports The title compound, C(13)H(14)NO(2)F(3), crystallises with two molecules, A and B, in the asymmetric unit, with similar conformations. The dihedral angles between the piperidine and phenyl rings are 83.76 (2) and 75.23 (2)° in molecules A and B, respectively. The bond-angle sums around the N atoms [359.1 and 359.7° for molecules A and B, respectively] indicate sp (2) hybridization for these atoms. In the crystal, O—H⋯O hydrogen bonds link the molecules into separate [100] chains of A and B molecules. The chains are cross-linked by C—H⋯O interactions, generating alternating (001) sheets of A and B molecules. International Union of Crystallography 2015-09-26 /pmc/articles/PMC4647357/ /pubmed/26594481 http://dx.doi.org/10.1107/S205698901501765X Text en © Revathi et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Data Reports Revathi, B. K. Reuben Jonathan, D. Kalai Sevi, K. Dhanalakshmi, K. Usha, G. Crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone |
| title | Crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone |
| title_full | Crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone |
| title_fullStr | Crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone |
| title_full_unstemmed | Crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone |
| title_short | Crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone |
| title_sort | crystal structure of (4-hydroxypiperidin-1-yl)[4-(trifluoromethyl)phenyl]methanone |
| topic | Data Reports |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647357/ https://www.ncbi.nlm.nih.gov/pubmed/26594481 http://dx.doi.org/10.1107/S205698901501765X |
| work_keys_str_mv | AT revathibk crystalstructureof4hydroxypiperidin1yl4trifluoromethylphenylmethanone AT reubenjonathand crystalstructureof4hydroxypiperidin1yl4trifluoromethylphenylmethanone AT kalaisevik crystalstructureof4hydroxypiperidin1yl4trifluoromethylphenylmethanone AT dhanalakshmik crystalstructureof4hydroxypiperidin1yl4trifluoromethylphenylmethanone AT ushag crystalstructureof4hydroxypiperidin1yl4trifluoromethylphenylmethanone |