Global analysis of physical and functional RNA targets of hnRNP L reveals distinct sequence and epigenetic features of repressed and enhanced exons

HnRNP L is a ubiquitous splicing-regulatory protein that is critical for the development and function of mammalian T cells. Previous work has identified a few targets of hnRNP L-dependent alternative splicing in T cells and has described transcriptome-wide association of hnRNP L with RNA. However, a...

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Detalles Bibliográficos
Autores principales: Cole, Brian S., Tapescu, Iulia, Allon, Samuel J., Mallory, Michael J., Qiu, Jinsong, Lake, Robert J., Fan, Hua-Ying, Fu, Xiang-Dong, Lynch, Kristen W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647460/
https://www.ncbi.nlm.nih.gov/pubmed/26437669
http://dx.doi.org/10.1261/rna.052969.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647460/
https://www.ncbi.nlm.nih.gov/pubmed/26437669
http://dx.doi.org/10.1261/rna.052969.115

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