Cargando…

Neuropilin-2 induced by transforming growth factor-β augments migration of hepatocellular carcinoma cells

BACKGROUND: Hepatocellular carcinoma (HCC) is the most common form of liver cancer and the third most lethal cancer worldwide. The epithelial to mesenchymal transition (EMT) describes the transformation of well-differentiated epithelial cells to a de-differentiated phenotype and plays a central role...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wittmann, Philipp, Grubinger, Markus, Gröger, Christian, Huber, Heidemarie, Sieghart, Wolfgang, Peck-Radosavljevic, Markus, Mikulits, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647494/ https://www.ncbi.nlm.nih.gov/pubmed/26573807 http://dx.doi.org/10.1186/s12885-015-1919-0

Ejemplares similares

Transforming Growth Factor‐β and Axl Induce CXCL5 and Neutrophil Recruitment in Hepatocellular Carcinoma
por: Haider, Christine, et al.
Publicado: (2018)

Meta-Analysis of Gene Expression Signatures Defining the Epithelial to Mesenchymal Transition during Cancer Progression
por: Gröger, Christian J., et al.
Publicado: (2012)

Transforming Growth Factor-β Drives the Transendothelial Migration of Hepatocellular Carcinoma Cells
por: Koudelkova, Petra, et al.
Publicado: (2017)

Cancer and liver cirrhosis: implications on prognosis and management
por: Pinter, Matthias, et al.
Publicado: (2016)

The impact of thyroid hormones on patients with hepatocellular carcinoma
por: Pinter, Matthias, et al.
Publicado: (2017)

TGF-β dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells
por: Proell, Verena, et al.
Publicado: (2007)

Short- and long-term effects of transarterial chemoembolization on portal hypertension in patients with hepatocellular carcinoma
por: Scheiner, Bernhard, et al.
Publicado: (2019)

La enhances IRES-mediated translation of laminin B1 during malignant epithelial to mesenchymal transition
por: Petz, Michaela, et al.
Publicado: (2012)

PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition
por: Petz, Michaela, et al.
Publicado: (2012)

Review article: systemic treatment of hepatocellular carcinoma
por: Pinter, Matthias, et al.
Publicado: (2018)

The leader region of Laminin B1 mRNA confers cap-independent translation
por: Petz, Michaela, et al.
Publicado: (2007)

PRAME Is a Novel Target of Tumor-Intrinsic Gas6/Axl Activation and Promotes Cancer Cell Invasion in Hepatocellular Carcinoma
por: Hedrich, Viola, et al.
Publicado: (2023)

Oxidative stress mediates an increased formation of vascular endothelial growth factor in human hepatocarcinoma cells exposed to erlotinib
por: Rohr-Udilova, Nataliya, et al.
Publicado: (2017)

Immunotherapy for advanced hepatocellular carcinoma: a focus on special subgroups
por: Pinter, Matthias, et al.
Publicado: (2021)

EGFR has a tumor-promoting role in liver macrophages during hepatocellular carcinoma formation
por: Lanaya, Hanane, et al.
Publicado: (2014)

Synergism of the receptor tyrosine kinase Axl with ErbB receptors mediates resistance to regorafenib in hepatocellular carcinoma
por: Breitenecker, Kristina, et al.
Publicado: (2023)

Time to stop using hepatic arterial infusion chemotherapy (HAIC) for advanced hepatocellular carcinoma?—the SCOOP-2 trial experience
por: Peck-Radosavljevic, Markus, et al.
Publicado: (2020)

Morphometric Analysis of Mast Cells in Tumor Predicts Recurrence of Hepatocellular Carcinoma After Liver Transplantation
por: Rohr‐Udilova, Nataliya, et al.
Publicado: (2021)

Accuracy of novel diagnostic biomarkers for hepatocellular carcinoma: An update for clinicians (Review)
por: Reichl, Patrick, et al.
Publicado: (2016)

The value of [(11)C]-acetate PET and [(18)F]-FDG PET in hepatocellular carcinoma before and after treatment with transarterial chemoembolization and bevacizumab
por: Li, Shuren, et al.
Publicado: (2017)

Proton Pump Inhibitor Intake neither Predisposes to Spontaneous Bacterial Peritonitis or Other Infections nor Increases Mortality in Patients with Cirrhosis and Ascites
por: Mandorfer, Mattias, et al.
Publicado: (2014)

Octreotide treatment of patients with hepatocellular carcinoma - a retrospective single centre controlled study
por: Schöniger-Hekele, Maximilian, et al.
Publicado: (2009)

Neuropilin-1 Acts as a Receptor for Complement Split Products
por: Battin, Claire, et al.
Publicado: (2019)

Drug Therapy for Advanced-Stage Liver Cancer
por: Peck-Radosavljevic, Markus
Publicado: (2014)

Editorial
por: Peck-Radosavljevic, Markus
Publicado: (2020)

Dynamics of Axl Receptor Shedding in Hepatocellular Carcinoma and Its Implication for Theranostics
por: Holstein, Elisa, et al.
Publicado: (2018)

Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma
por: Bellomo, Claudia, et al.
Publicado: (2017)

LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation
por: Morén, Anita, et al.
Publicado: (2019)

Long-term remission in advanced stage hepatocellular carcinoma? A chance for cure?
por: Pinter, Matthias, et al.
Publicado: (2018)

Intrinsic and Extrinsic Control of Hepatocellular Carcinoma by TAM Receptors
por: Hedrich, Viola, et al.
Publicado: (2021)

Programmed cell death protein‐1 (PD‐1)‐targeted immunotherapy in advanced hepatocellular carcinoma: efficacy and safety data from an international multicentre real‐world cohort
por: Scheiner, Bernhard, et al.
Publicado: (2019)

Neuropilin1 silencing impairs the proliferation and migration of cells in pancreatic cancer
por: He, Li‐Hong, et al.
Publicado: (2020)

Neuropilin-1 is a receptor for transforming growth factor β-1, activates its latent form, and promotes regulatory T cell activity
por: Glinka, Yelena, et al.
Publicado: (2008)

Elevated expression of neuropilin-2 associated with unfavorable prognosis in hepatocellular carcinoma
por: Dong, Xiaogang, et al.
Publicado: (2017)

Transjugular intrahepatic portosystemic shunts (TIPS) for the prevention of variceal re-bleeding – A two decades experience
por: Bucsics, Theresa, et al.
Publicado: (2018)

The non-invasive serum biomarker soluble Axl accurately detects advanced liver fibrosis and cirrhosis
por: Staufer, Katharina, et al.
Publicado: (2017)

Changes in the Epidemiology of Hepatocellular Carcinoma in Carinthia, Austria, 2012–2023
por: Hucke, Florian, et al.
Publicado: (2023)

NADPH Oxidase NOX4 Mediates Stellate Cell Activation and Hepatocyte Cell Death during Liver Fibrosis Development
por: Sancho, Patricia, et al.
Publicado: (2012)

Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity
por: Jia, H, et al.
Publicado: (2010)

Semaphorin 3F and Neuropilin-2 Control the Migration of Human T-Cell Precursors
por: Mendes-da-Cruz, Daniella Arêas, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6g2vl01o4cq1lstfi2dm0qgqns