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Genomic mutational analysis of the impact of the classical strain improvement program on β–lactam producing Penicillium chrysogenum
BACKGROUND: Penicillium chrysogenum is a filamentous fungus that is employed as an industrial producer of β–lactams. The high β–lactam titers of current strains is the result of a classical strain improvement program (CSI) starting with a wild-type like strain more than six decades ago. This involve...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647614/ https://www.ncbi.nlm.nih.gov/pubmed/26572918 http://dx.doi.org/10.1186/s12864-015-2154-4 |