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Activation of MEK2 is sufficient to induce skin papilloma formation in transgenic zebrafish

BACKGROUND: Mutations in mitogen-activated protein kinase (MAPK) kinase 1 (MEK1) that occur during cell proliferation and tumor formation are well described. Information on the roles of MEK2 in these effects is still limited. We established a constitutive MEK2 transgenic zebrafish, Tg(krt14:MEK2S219...

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Detalles Bibliográficos
Autores principales:	Chou, Chih-Ming, Chen, Yi-Chung, Su, San, Chen, Gen-Der, Huang, Kai-Yun, Lien, Huang-Wei, Huang, Chang-Jen, Cheng, Chia-Hsiung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647631/ https://www.ncbi.nlm.nih.gov/pubmed/26572230 http://dx.doi.org/10.1186/s12929-015-0207-2

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