Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders

BACKGROUND: Proper neuronal function requires tight control of gene dosage, and failure of this process underlies the pathogenesis of multiple neuropsychiatric disorders. The SHANK3 gene encoding core scaffolding proteins at glutamatergic postsynapse is a typical dosage-sensitive gene, both deletion...

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Detalles Bibliográficos
Autores principales: Choi, Su-Yeon, Pang, Kaifang, Kim, Joo Yeon, Ryu, Jae Ryun, Kang, Hyojin, Liu, Zhandong, Kim, Won-Ki, Sun, Woong, Kim, Hyun, Han, Kihoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647645/
https://www.ncbi.nlm.nih.gov/pubmed/26572867
http://dx.doi.org/10.1186/s13041-015-0165-3

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