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RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships

BACKGROUND: RNA:DNA hybrids represent a non-canonical nucleic acid structure that has been associated with a range of human diseases and potential transcriptional regulatory functions. Mapping of RNA:DNA hybrids in human cells reveals them to have a number of characteristics that give insights into...

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Detalles Bibliográficos
Autores principales: Nadel, Julie, Athanasiadou, Rodoniki, Lemetre, Christophe, Wijetunga, N. Ari, Ó Broin, Pilib, Sato, Hanae, Zhang, Zhengdong, Jeddeloh, Jeffrey, Montagna, Cristina, Golden, Aaron, Seoighe, Cathal, Greally, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647656/
https://www.ncbi.nlm.nih.gov/pubmed/26579211
http://dx.doi.org/10.1186/s13072-015-0040-6