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Major differential gene regulation in Coxiella burnetii between in vivo and in vitro cultivation models
BACKGROUND: Coxiella burnetii is the causative agent of the zoonotic disease Q fever. As it is an intracellular pathogen, infection by C. burnetii requires adaptation to its eukaryotic host and intracellular environment. The recently developed cell-free medium also allows the bacteria to propagate w...
Autores principales: | Kuley, Runa, Bossers-deVries, Ruth, Smith, Hilde E., Smits, Mari A., Roest, Hendrik I. J., Bossers, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647677/ https://www.ncbi.nlm.nih.gov/pubmed/26572556 http://dx.doi.org/10.1186/s12864-015-2143-7 |
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