Target gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation

BACKGROUND: We previously reported that the target genes in sporadic mismatch repair (MMR)-deficient colorectal carcinomas (CRCs) in the distal colon differ from those occurring elsewhere in the colon. This study aimed to compare the target gene mutational pattern in microsatellite instability (MSI)...

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Detalles Bibliográficos
Autores principales: Pinheiro, Manuela, Pinto, Carla, Peixoto, Ana, Veiga, Isabel, Lopes, Paula, Henrique, Rui, Baldaia, Helena, Carneiro, Fátima, Seruca, Raquel, Tomlinson, Ian, Kovac, Michal, Heinimann, Karl, Teixeira, Manuel R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Genetics & Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647680/
https://www.ncbi.nlm.nih.gov/pubmed/26247575
http://dx.doi.org/10.1038/bjc.2015.281

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