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Effects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice

BACKGROUND: Growth arrest and DNA damage-inducible protein 34 (GADD34/Ppp1r15a) is a family of GADD proteins that are induced by DNA damage. GADD34 protein has been suggested to regulate inflammation or host defense systems. However, the in vivo function of GADD34 in inflammation is still unclear. L...

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Detalles Bibliográficos
Autores principales: Tanaka, Yuriko, Ito, Sachiko, Oshino, Reina, Chen, Nana, Nishio, Naomi, Isobe, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647681/
https://www.ncbi.nlm.nih.gov/pubmed/26196182
http://dx.doi.org/10.1038/bjc.2015.263