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Next-generation sequencing of tyrosine kinase inhibitor-resistant non-small-cell lung cancers in patients harboring epidermal growth factor-activating mutations

BACKGROUND: The aim of this study was to detect the epidermal growth factor receptor (EGFR)-activating mutations and other oncogene alterations in patients with non-small-cell lung cancers (NSCLC) who experienced a treatment failure in response to EGFR-tyrosine kinase inhibitors (TKIs) with a next g...

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Detalles Bibliográficos
Autores principales: Masago, Katsuhiro, Fujita, Shiro, Muraki, Miho, Hata, Akito, Okuda, Chiyuki, Otsuka, Kyoko, Kaji, Reiko, Takeshita, Jumpei, Kato, Ryoji, Katakami, Nobuyuki, Hirata, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647703/
https://www.ncbi.nlm.nih.gov/pubmed/26572169
http://dx.doi.org/10.1186/s12885-015-1925-2