Cargando…

Comparative efficacy of esomeprazole and omeprazole: Racemate to single enantiomer switch

BACKGROUND: Both omeprazole and its S enantiomer (esomeprazole) have been available and used to treat symptoms of gastroesophageal reflux disease (GERD) and conditions associated with excessive stomach acid secretion for more than a decade. Controversy exists over improved efficacy of S enantiomer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asghar, Waheed, Pittman, Elliot, Jamali, Fakhreddin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647708/ https://www.ncbi.nlm.nih.gov/pubmed/26573220 http://dx.doi.org/10.1186/s40199-015-0133-6

Ejemplares similares

A comparative Analysis of In Vitro and In Vivo Efficacies of the Enantiomers of Thioridazine and Its Racemate
por: Christensen, Jørn B., et al.
Publicado: (2013)

Comparative single dose pharmacokinetics and metabolism of racemic primaquine and its enantiomers in human volunteers
por: Khan, Washim, et al.
Publicado: (2022)

Evaluation of Trials Comparing Single-Enantiomer Drugs to Their Racemic Precursors: A Systematic Review
por: Long, Aaron S., et al.
Publicado: (2021)

Strategies for chiral separation: from racemate to enantiomer
por: Sui, Jingchen, et al.
Publicado: (2023)

Time-dependent association between omeprazole and esomeprazole and hospitalization due to hyponatremia
por: Issa, Issa, et al.
Publicado: (2022)

Oral esomeprazole vs injectable omeprazole for the prevention of hemorrhage after endoscopic submucosal dissection
por: Uchiyama, Takashi, et al.
Publicado: (2017)

Pressure Dependence of the Crystallization Rate for the S-Enantiomer and a Racemic Mixture of Ibuprofen
por: Koperwas, Kajetan, et al.
Publicado: (2021)

Comparative metabolism and tolerability of racemic primaquine and its enantiomers in human volunteers during 7-day administration
por: Khan, Washim, et al.
Publicado: (2023)

Omeprazole- and Esomeprazole-associated Hypomagnesaemia: Data Mining of the Public Version of the FDA Adverse Event Reporting System
por: Tamura, Takao, et al.
Publicado: (2012)

Differential Effects of Omeprazole and Lansoprazole Enantiomers on Aryl Hydrocarbon Receptor in Human Hepatocytes and Cell Lines
por: Novotna, Aneta, et al.
Publicado: (2014)

A Case-Control Study of Esomeprazole Plus Rebamipide vs. Omeprazole Plus Rebamipide on Post-ESD Gastric Ulcers
por: Bunno, Maki, et al.
Publicado: (2013)

Racemization-free synthesis of Nα-2-thiophenoyl-phenylalanine-2-morpholinoanilide enantiomers and their antimycobacterial activity
por: Mann, Lea, et al.
Publicado: (2021)

Rotaxanes with dynamic mechanical chirality: Systematic studies on synthesis, enantiomer separation, racemization, and chiral-prochiral interconversion
por: Ishiwari, Fumitaka, et al.
Publicado: (2022)

CYP2C19 loss‐of‐function alleles and use of omeprazole or esomeprazole increase the risk of cardiovascular outcomes in patients using clopidogrel
por: Ramste, Markus, et al.
Publicado: (2023)

Ensayo clínico para evaluar la eficacia del esomeprazol vs omeprazol en la enfermedad por reflujo gastroesofágico
por: Aguirre Cardoza, Rafael
Publicado: (2003)

High-Pressure Crystallization and Thermodynamic Stability Study on the Resolution of High-Density Enantiomers from Low-Density Racemates
por: Roszak, Kinga, et al.
Publicado: (2023)

Antipsychotic Benzamides Amisulpride and LB-102 Display Polypharmacy as Racemates, S Enantiomers Engage Receptors D(2) and D(3), while R Enantiomers Engage 5-HT(7)
por: Grattan, Vincent, et al.
Publicado: (2019)

Impact of enantiomer‐specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac: A pooled analysis
por: Cloesmeijer, Michael E., et al.
Publicado: (2020)

Comparative Pharmacokinetics/Pharmacodynamics of Fixed-Dose Combination of Esomeprazole and Calcium Carbonate (AD-206) to the Conventional Esomeprazole
por: Bae, Sungyeun, et al.
Publicado: (2021)

Racemic Salsolinol and its Enantiomers Act as Agonists of the μ-Opioid Receptor by Activating the Gi Protein-Adenylate Cyclase Pathway
por: Berríos-Cárcamo, Pablo, et al.
Publicado: (2017)

Determination and Pharmacokinetics of Omeprazole Enantiomers in Human Plasma and Oral Fluid Utilizing Microextraction by Packed Sorbent and Liquid Chromatography-Tandem Mass Spectrometry
por: Ahmed, Hytham, et al.
Publicado: (2021)

Randomized Controlled Trial Comparing the Efficacy of Sustained-Release Formula of Mosapride-Plus-Esomeprazole Combination Therapy to Esomeprazole Monotherapy in Patients with Gastroesophageal Reflux Disease
por: Jeon, Hye Kyung, et al.
Publicado: (2022)

Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH
por: Iida, Hiroshi, et al.
Publicado: (2012)

Comparative Efficacy of Tegoprazan vs Esomeprazole/Sodium Bicarbonate for the Treatment of Helicobacter pylori Infection
por: Park, Chan Hyuk, et al.
Publicado: (2023)

Development and validation of a stability indicating method for the enantioselective estimation of omeprazole enantiomers in the enteric-coated formulations by high-performance liquid chromatography
por: Vyas, Samir, et al.
Publicado: (2011)

Omeprazole and Lansoprazole Enantiomers Induce CYP3A4 in Human Hepatocytes and Cell Lines via Glucocorticoid Receptor and Pregnane X Receptor Axis
por: Novotna, Aneta, et al.
Publicado: (2014)

Induction of Erythrocyte Shrinkage by Omeprazole
por: Naveed, Ayesha, et al.
Publicado: (2020)

Randomized controlled trial to evaluate the efficacy and safety of fexuprazan compared with esomeprazole in erosive esophagitis
por: Lee, Kang Nyeong, et al.
Publicado: (2022)

Racemic salbutamol and levosalbutamol in mild persistent asthma: A comparative study of efficacy and safety
por: Maiti, Rituparna, et al.
Publicado: (2011)

Efficacy of omeprazole, famotidine, mosapride and teprenone in patients with upper gastrointestinal symptoms: an omeprazole-controlled randomized study (J-FOCUS)
por: Sakurai, Kouichi, et al.
Publicado: (2012)

A Double-blind, Randomized, Multicenter Clinical Trial Investigating the Efficacy and Safety of Esomeprazole Single Therapy Versus Mosapride and Esomeprazole Combined Therapy in Patients with Esophageal Reflux Disease
por: Lee, Ju Yup, et al.
Publicado: (2017)

Rabeprazole and esomeprazole in mild-to-moderate erosive gastroesophageal reflux disease: A comparative study of efficacy and safety
por: Maiti, Rituparna, et al.
Publicado: (2011)

Reduction in the rate of postoperative delirium by switching from famotidine to omeprazole in Japanese hepatectomized recipients
por: Yamasaki, Miho, et al.
Publicado: (2019)

Efficacy of esomeprazole in treating acid-related diseases in Japanese populations
por: Sugimoto, Mitsushige, et al.
Publicado: (2012)

Conversion of Racemic Alkyl Aryl Sulfoxides into Pure Enantiomers Using a Recycle Photoreactor: Tandem Use of Chromatography on Chiral Support and Photoracemization on Solid Support
por: Tozawa, Kumi, et al.
Publicado: (2023)

Effect of esomeprazole on the pharmacokinetics of carbamazepine
por: Medhi, Bikash, et al.
Publicado: (2011)

Night‐time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole
por: Yang, Eunsol, et al.
Publicado: (2022)

Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model
por: Nelson, Christina, et al.
Publicado: (2017)

Comparative pharmacokinetics and tissue distribution of primaquine enantiomers in mice
por: Fasinu, Pius S., et al.
Publicado: (2022)

Esomeprazole and apixaban pharmacokinetic interactions in healthy rats
por: Jaber, Ali, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0ckeeu0h0f7t2g9gkdeqvmdmct