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Induction of proto-oncogene BRF2 in breast cancer cells by the dietary soybean isoflavone daidzein

BACKGROUND: BRF2 is a transcription factor required for synthesis of a small group of non-coding RNAs by RNA polymerase III. Overexpression of BRF2 can transform human mammary epithelial cells. In both breast and lung cancers, the BRF2 gene is amplified and overexpressed and may serve as an oncogeni...

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Detalles Bibliográficos
Autores principales: Koo, Jana, Cabarcas-Petroski, Stephanie, Petrie, John L., Diette, Nicole, White, Robert J., Schramm, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647806/
https://www.ncbi.nlm.nih.gov/pubmed/26573593
http://dx.doi.org/10.1186/s12885-015-1914-5