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Induction of proto-oncogene BRF2 in breast cancer cells by the dietary soybean isoflavone daidzein
BACKGROUND: BRF2 is a transcription factor required for synthesis of a small group of non-coding RNAs by RNA polymerase III. Overexpression of BRF2 can transform human mammary epithelial cells. In both breast and lung cancers, the BRF2 gene is amplified and overexpressed and may serve as an oncogeni...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647806/ https://www.ncbi.nlm.nih.gov/pubmed/26573593 http://dx.doi.org/10.1186/s12885-015-1914-5 |