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Pretreatment of parecoxib attenuates hepatic ischemia/reperfusion injury in rats

BACKGROUND: Previous studies showed that cyclooxygenase(COX) was involved in ischemia/reperfusion (I/R) injuries. Parecoxib, a selective inhibitor for COX −2, has been shown to have protective properties in reducing I/R injury in the heart, kidney and brain. The aim of this study was to investigate...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Ma, Yi, Xu, Kang-Qing, Huang, Wen-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647808/
https://www.ncbi.nlm.nih.gov/pubmed/26577339
http://dx.doi.org/10.1186/s12871-015-0147-0