HIF2α is involved in the expansion of CXCR4-positive cancer stem-like cells in renal cell carcinoma

BACKGROUND: Hypoxia and the subsequent activation of hypoxia-inducible factor-2α (HIF2α) contribute to the progression of a variety of cancers. However, their role in the generation of renal cell carcinoma-derived stem cells has not been fully addressed. METHODS: A sphere formation assay, cell proli...

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Detalles Bibliográficos
Autores principales: Micucci, Carla, Matacchione, Giulia, Valli, Debora, Orciari, Silvia, Catalano, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647880/
https://www.ncbi.nlm.nih.gov/pubmed/26439684
http://dx.doi.org/10.1038/bjc.2015.338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647880/
https://www.ncbi.nlm.nih.gov/pubmed/26439684
http://dx.doi.org/10.1038/bjc.2015.338

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