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Total synthesis of (+)-gelsemine via an organocatalytic Diels–Alder approach
The structurally complex alkaloid gelsemine was previously thought to have no significant biological activities, but a recent study has shown that it has potent and specific antinociception in chronic pain. While this molecule has attracted significant interests from the synthetic community, an effi...
Autores principales: | Chen, Xiaoming, Duan, Shengguo, Tao, Cheng, Zhai, Hongbin, Qiu, Fayang G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647982/ https://www.ncbi.nlm.nih.gov/pubmed/25995149 http://dx.doi.org/10.1038/ncomms8204 |
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