Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics

The development of more active C–H oxidation catalysts has inspired a rapid, scalable, and stereoselective assembly of multifunctional piperazines through a [3+3] coupling of azomethine ylides. A combination of visible-light irradiation and aluminum organometallics is essential to promote this trans...

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Detalles Bibliográficos
Autores principales: Suárez-Pantiga, Samuel, Colas, Kilian, Johansson, Magnus J, Mendoza, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648034/
https://www.ncbi.nlm.nih.gov/pubmed/26337253
http://dx.doi.org/10.1002/anie.201505608
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author Suárez-Pantiga, Samuel
Colas, Kilian
Johansson, Magnus J
Mendoza, Abraham
author_facet Suárez-Pantiga, Samuel
Colas, Kilian
Johansson, Magnus J
Mendoza, Abraham
author_sort Suárez-Pantiga, Samuel
collection PubMed
description The development of more active C–H oxidation catalysts has inspired a rapid, scalable, and stereoselective assembly of multifunctional piperazines through a [3+3] coupling of azomethine ylides. A combination of visible-light irradiation and aluminum organometallics is essential to promote this transformation, which introduces visible-light photochemistry of main-group organometallics and sets the basis for new and promising catalysts.
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spelling pubmed-46480342015-11-24 Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics Suárez-Pantiga, Samuel Colas, Kilian Johansson, Magnus J Mendoza, Abraham Angew Chem Int Ed Engl Communications The development of more active C–H oxidation catalysts has inspired a rapid, scalable, and stereoselective assembly of multifunctional piperazines through a [3+3] coupling of azomethine ylides. A combination of visible-light irradiation and aluminum organometallics is essential to promote this transformation, which introduces visible-light photochemistry of main-group organometallics and sets the basis for new and promising catalysts. WILEY-VCH Verlag 2015-11-16 2015-09-04 /pmc/articles/PMC4648034/ /pubmed/26337253 http://dx.doi.org/10.1002/anie.201505608 Text en © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. https://creativecommons.org/licenses/by-nc/4.0/ © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Communications
Suárez-Pantiga, Samuel
Colas, Kilian
Johansson, Magnus J
Mendoza, Abraham
Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics
title Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics
title_full Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics
title_fullStr Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics
title_full_unstemmed Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics
title_short Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics
title_sort scalable synthesis of piperazines enabled by visible-light irradiation and aluminum organometallics
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648034/
https://www.ncbi.nlm.nih.gov/pubmed/26337253
http://dx.doi.org/10.1002/anie.201505608
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AT johanssonmagnusj scalablesynthesisofpiperazinesenabledbyvisiblelightirradiationandaluminumorganometallics
AT mendozaabraham scalablesynthesisofpiperazinesenabledbyvisiblelightirradiationandaluminumorganometallics

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