Enzymology of Pyran Ring A Formation in Salinomycin Biosynthesis

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Tetrahydropyran rings are a common feature of complex polyketide natural products, but much remains to be learned about the enzymology of their formation. The enzyme SalBIII from the salinomycin biosynthetic pathway resembles other polyether epoxide hydrolases/cyclases of the MonB family, but SalBII...

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Detalles Bibliográficos
Autores principales: Luhavaya, Hanna, Dias, Marcio V B, Williams, Simon R, Hong, Hui, de Oliveira, Luciana G, Leadlay, Peter F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648038/
https://www.ncbi.nlm.nih.gov/pubmed/26377145
http://dx.doi.org/10.1002/anie.201507090

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