Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial

BACKGROUND: HIV-1 infection is associated with increased risk of tuberculosis and a safe and effective vaccine would assist control measures. We assessed the safety, immunogenicity, and efficacy of a candidate tuberculosis vaccine, modified vaccinia virus Ankara expressing antigen 85A (MVA85A), in a...

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Detalles Bibliográficos
Autores principales: Ndiaye, Birahim Pierre, Thienemann, Friedrich, Ota, Martin, Landry, Bernard S, Camara, Makhtar, Dièye, Siry, Dieye, Tandakha Ndiaye, Esmail, Hanif, Goliath, Rene, Huygen, Kris, January, Vanessa, Ndiaye, Ibrahima, Oni, Tolu, Raine, Michael, Romano, Marta, Satti, Iman, Sutton, Sharon, Thiam, Aminata, Wilkinson, Katalin A, Mboup, Souleymane, Wilkinson, Robert J, McShane, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648060/
https://www.ncbi.nlm.nih.gov/pubmed/25726088
http://dx.doi.org/10.1016/S2213-2600(15)00037-5

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