Role of KRAS-LCS6 polymorphism in advanced NSCLC patients treated with erlotinib or docetaxel in second line treatment (TAILOR)

MicroRNAs were described to target mRNA and regulate the transcription of genes involved in processes de-regulated in tumorigenesis, such as proliferation, differentiation and survival. In particular, the miRNA let-7 has been suggested to regulate the expression of the KRAS gene, a common mutated ge...

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Detalles Bibliográficos
Autores principales: Ganzinelli, Monica, Rulli, Eliana, Caiola, Elisa, Chiara Garassino, Marina, Broggini, Massimo, Copreni, Elena, Piva, Sheila, Longo, Flavia, Labianca, Roberto, Bareggi, Claudia, Agnese Fabbri, Maria, Martelli, Olga, Fagnani, Daniele, Cristina Locatelli, Maria, Bertolini, Alessandro, Valmadre, Giuseppe, Pavese, Ida, Calcagno, Anna, Giuseppa Sarobba, Maria, Marabese, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648064/
https://www.ncbi.nlm.nih.gov/pubmed/26573509
http://dx.doi.org/10.1038/srep16331

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