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Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment
Recent studies have revealed extensive genetic and non-genetic variation across different geographical regions of a tumor or throughout different stages of tumor progression, which is referred to as intra-tumor heterogeneity. Several causes contribute to this phenomenon, including genomic instabilit...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648179/ https://www.ncbi.nlm.nih.gov/pubmed/26388155 http://dx.doi.org/10.1038/aps.2015.92 |