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Cytotoxic granule secretion by lymphocytes and its link to immune homeostasis
The granule-dependent cytotoxic activity of T and natural killer lymphocytes has progressively emerged as an important effector pathway not only for host defence but also for immune regulation. The analysis of an early-onset, severe, primary immune dysregulatory syndrome known as hemophagocytic lymp...
Autores principales: | de Saint Basile, Geneviève, Sepulveda, Fernando E., Maschalidi, Sophia, Fischer, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648190/ https://www.ncbi.nlm.nih.gov/pubmed/26594351 http://dx.doi.org/10.12688/f1000research.6754.1 |
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